Sphingolipid Synthesis Metabolism

Quantification of sphingolipid biosynthesis phosphate intermediates, sphinganines, ceramides, sphingomyelins, sulfatides, cerebrosides and gangliosides by UPLC-MRM/MS.

Minimum Amount Required

Tissue 10 mg
Cell 2x10^6
Blood/plasma/serum 20 µL
Urine 50 µL
Plant N/A
Feces 5 mg
DBS 20 µL
cell medium

Pathways

Sphingolipid synthesis and metabolism
Lipidogenesis
Lipolysis

Academic Price

$400 1st sample; $120 each additional sample

Industry Price

$800 1st sample; $240 each additional sample

Compound Classes

synthesis precursors, intermediate phosphates, ceramides, sphingomyelins, cerabrosides and selected gangliosides

Compounds

3-Keto Sphinganine
1-Desoxymethylsphinganine
1-Deoxysphinganine
Sphinganine (d16:0
Sphinganine (d18:0)
Sphinganine (d20:0)
Sphinganine-1-phosphate (d18:0)
C02 Dihydroceramide (d18:0/2:0)
C06 Dihydroceramide (d18:0/6:0)
C08 Dihydroceramide (d18:0/8:0)
C12 Dihydroceramide (d18:0/12:0)
C14 dihydroceramide (d18:0/14:0)
C16 Dihydroceramide (d18:0/16:0)
C16 dihydro Ceramide (d18:0/16:0)
C17 dihydro Ceramide (d18:0/17:0)
C18 Dihydroceramide (d18:0/18:0)
C18:1 Dihydroceramide (d18:0/18:1(9Z))
C24 Dihydroceramide (d18:0/24:0)
C24:1 Dihydroceramide (d18:0/24:1(15Z))
C16 Dihydroceramide-1-Phosphate (d18:0/16:0)
C24 Dihydroceramide-1-Phosphate (d18:0/24:0)
C06 Ceramide (d18:1/6:0)
C08 Ceramide (d18:1.8:0)
C10 Ceramide (d18:1/10:0)
C12 Ceramide (d18:1/12:0)
C14 Ceramide (d18:1/14:0)
C16 Ceramide (d18:1/16:0)
C18 Ceramide (d18:1/18:0)
C18:1 Ceramide (d18:1/18:1(9Z))
C19 Ceramide (d18:1/19:0)
C20 Ceramide (d18:1/20:0)
C22 Ceramide (d18:1/22:0)
C24 Ceramide (d18:1/24:0)
C24:1 Ceramide (d18:1/24:1(15Z))
C16 Ceramide-1-phosphate (d18:1/16:0)
C18:1 Ceramide-1-Phosphate (d18:1/18:1(9Z))
Sphingosine (d18:1)
Sphingosine-1-phosphate (S1P) (d18:1)
Sphingosine-1-phosphate (d16:1)
Sphingosine-1-phosphate (d17:1)
12:0 Dihydro SM (d18:0/12:0)
Lyso SM (d17:1)
Lyso SM(d18:1)
Lyso SM (dihydro) (d18:0)
06:0 SM (d18:1/6:0)
12:0 SM (d18:1/12:0)
14:0 SM (d18:1/14:0)
C16 Sphingomyelin (d18:1/16:0)
C16:1 Sphingomyelin(SM) (d18:1/16:1(9Z))
C17 Sphingomyelin (d18:1/17:0)
C18 Sphingomyelin (d18:1/18:0)
C18:1 Sphingomyelin (d18:1/18:1)
C20:0 Sphingomyelin (d18:1/20:0)
C22:0 Sphingomyelin (d18:1/22:0)
Sphingomyelin(SM) (d18:1/24:0)
Sphingomyelin(SM) (d18:1/24:1)
Glucosyl Sphingosine (d18:1)
Glucosyl (ß) Sphingosine (d20:1)
C8 Glucosyl(ß) Ceramide (d18:1/8:0)
C12 Glucosyl(ß) Ceramide (d18:1/12:0)
C16 Glucosyl(ß) Ceramide (d18:1/14:0)
C16 Glucosyl(ß) Ceramide (d18:1/16:0)
C18 Glucosyl(ß) Ceramide (d18:1/18:0)
C18:1 Glucosyl(ß) Ceramide (d18:1/18:1(9Z))
C18 Glucosyl(ß) Ceramide (d18:1/20:0)
C18 Glucosyl(ß) Ceramide (d18:1/22:0)
C24:1 Glucosyl(ß) Ceramide (d18:1/24:0)
C24:1 Glucosyl(ß) Ceramide (d18:1/24:1(15Z))
Galactosylsphingosine (d18:1)
C08 Galactosyl(ß) Ceramide (d18:1/08:0)
C12 Galactosyl(ß) Ceramide (d18:1/12:0)
C16 Galactosyl(ß) Ceramide (d18:1/16:0)
C18 Galactosyl(ß) Ceramide (d18:1/18:0)
C18:1 Galactosyl(ß) Ceramide (d18:1/18:1(9Z))
C24:1 Galactosyl(ß) Ceramide (d18:1/24:1(15Z))
Lactosyl(ß) Sphingosine (d18:1)
C08 Lactosyl(ß) Ceramide (d18:1/08:0)
C12 Lactosyl(ß) Ceramide (d18:1/12:0)
C16 Lactosyl(ß) Ceramide (d18:1/14:0)
C16 Lactosyl(ß) Ceramide (d18:1/16:0)
C18:1 Lactosyl(ß) Ceramide (d18:1/18:0)
C18:1 Lactosyl(ß) Ceramide (d18:1/18:1)
C18:1 Lactosyl(ß) Ceramide (d18:1/20:0)
C18:1 Lactosyl(ß) Ceramide (d18:1/22:0)
C24 Lactosyl(ß) Ceramide (d18:1/24:0)
C24:1 Lactosyl(ß) Ceramide (d18:1/24:1)
N-2'-OH C18 D-ribo Phytosphingosine
D-ribo-Phytosphingosine-1-Phosphate
N-16:0 Phytosphingosine (t18:0/16:0)
N-C18 Phytoceramide (t18:0/18:0)