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Folate Cycle /Methionine Cycle/Transsulfuration Pathway Assay
Quantification of metabolites in folate cycle, methione cycle, choline metabolism, transulfuration pathway and vitamin cofactors by LC-MS
Minimum Amount Required
Tissue 25 mg
Cell 5x10^6
Blood/plasma/serum 100 µL
Urine 100 µL
Plant 100 mg
Feces N/A
DBS N/A
Academic Price
$400 1st sample; $120 each additional sample
Industry Price
$800 1st sample; $240 each additional sample
Pathways
Folate cycle, methione cycle, cysteine synthesis and metabolism, choline and betaine degradation, transulfuration, methylation pathway
Compound Classes
Folates, SAM, SAH, dcSAM, vitamin Bs, reduced and oxidized glutathione, amino acids, cysteine, homocysteine, cystathionine
Compounds
Folate
Dihydrofolate (DHF)
Tetrahydrofolate (THF)
5-Methyl THF
SAH
SAM
dcSAM
Choline
Acetyl choline
Betaine
Cystathionine
Cysteine
Homocysteine
Cystine
Glutathione reduced (GSH)
Glutathione oxidized (GSSG)
Glycine
Homocysteine
Hypotaurine
Methionine
Serine
Homoserine
Taurine
Vitamin B2
(Vitamin B12)
Vitamin B6
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