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Aromatic amino acid/dopamine metabolism assay
Quantitation of all the known metabolites of aromatic amino acids (Tyr, Phe and Trp) metabolism and dopmaine synthesis and metabolism pathways by UPLC-MRM/MS
Minimum Amount Required
Blood/plasma/serum 50 µL
Cell 2x10^6
Tissue 20 mg
Cell medium 100 µL
Cecal content/feces 50 mg
Academic Price
$400 1st sample; $120 each additional sample
Industry Price
$800 1st sample; $240 each additional sample
Pathways
Tyr, Phe and Trp metabolism
dopamine synthesis and metabolism
Kynurenine pathway
host-gut indole metabolism
Compound Classes
64 metabolites involved in the Tyr/Phe/Trp metabolism, dopamine metabolism, Kynurenine pathway and indole metabolism
Compounds
Tyrosine
Tryptophan
Phenylalanine
Melatonin
5-Hydroxyindoleacetic acid (5-HIAA)
Phenylacetyl-L-Glutamine
4-Hydroxyphenylpyruvic acid
Homogentisic acid
N-Acetylserotonin
Serotonin (5-HT)
N-Methylphenethylamine
Synephrine
Vanillactic acid
Phenyllactic acid
Phenylpyruvic acid
3-Methoxytryptamine
5-hydroxy-N-methyl tryptamine
N-Methyltryptamine
Metanephrine (MN)
N-Acetyltyramine
DOPA (3-Hydroxytyrosine)
3,4-Dimethoxyphenethylamine
3-Methoxyt tyramine (3-MT)
3-O-Methyl-L-DOPA
5-Methoxytryptamine
DOPA methyl ester
3,4-Dihydroxyphenylacetic acid (DOPAC)
Dopamine
Epinephrine (adrenaline)
Homovanillic acid (HVA)
N-Methyltyramine
Norepinephrine (noradrenaline)
Normetanephrine (NMN)
Octopamine
Phenylethylamine
Tyramine
Tyrosine methyl ester
2-Methyl-L-DOPA
2-Picolinic acid
Tryptophol
5-Hydroxy tryptophol
5-Hydroxy tryptophan (5-HTP)
Xanthurenic Acid
Kynurenic Acid
3-Hydroxyanthranilic Acid (3-HAA)
3-Hydroxykynurenine
5-Aminovaleric acid
Kynurenine
Pipecolic acid
Anthranilic acid
3-(3-hydroxyphenyl)propionic acid (3-HPP)
4-Hydroxyphenyllactic acid
3,4-Dihydroxyphenyl pyruvic acid
3,4-Dihydroxyphenyl lactic acid
3,4-Dihydroxyphenyl glycol
3,4-Dihydroxyphenyl ethanol
3-(3,4-Dihydroxyphenyl)propionic acid
Indole 3-acetamide
Indole 3-acetic acid
Indole 3-acrylic acid
Indole 3-aldehyde
Indole 3-propionic acid
Indole 3-butyric acid
Indole 3-carboxylic acid
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