Aromatic amino acid/dopamine metabolism assay

Assay Overview

Quantitation of all the known metabolites of aromatic amino acids (Tyr, Phe and Trp) metabolism and dopmaine synthesis and metabolism pathways by UPLC-MRM/MS

Pathways:

Tyr, Phe and Trp metabolism
dopamine synthesis and metabolism
Kynurenine pathway
host-gut indole metabolism

Minimum Amount Required

Blood/plasma/serum 50 µL
Cell 2x10^6
Tissue 20 mg
Cell medium 100 µL
Cecal content/feces 50 mg

Compound Classes

Academic Pricing

$400 1st sample; $180 each additional sample

Industry Pricing

$800 1st sample; $360 each additional sample

Quantitation of >120 metabolites involved in synthesis, metabolism and degradation pathways of aromatic amino acids including Tyr, Phe, Trp and His by UPLC-MRM/MS

Compounds

1-Methyl histidine
1-Methylimidazole acetic acid
1-Phenylethylamine
2-Hydroxyphenyl acetic acid
2-Methyl hippuric acid
2-Phenylethylamine
2-Picolinic acid
3-(3-Hydroxyphenyl)-3-hydroxypropionic acid
3,4-dihydroxyphenyl acetaldehyde
3,4-Dihydroxyphenyl acetic acid
3,4-Dihydroxyphenyl ethanol
3,4-Dihydroxyphenyl glycol
3,4-Dihydroxyphenyl lactic acid
3,4-Dihydroxyphenyl propionic acid
3,4-Dihydroxyphenyl pyruvic acid
3,4-Dimethoxy phenethylamine
3-Hydroxy hippuric acid
3-Hydroxy kynurenine
3-Hydroxy tyramine
3-Hydroxyanthranilic acid
3-Hydroxyindole
3-Hydroxyphenyl propionic acid
3-Methoxy anthranilic acid
3-Methoxy tryptamine
3-Methoxy tyramine
3-Methoxy-4-hydroxyphenylglycol
3-Methyl histidine
3-Methyl-L-DOPA
4-Aminobenzoic acid
4-Hydroxy benzoic acid
4-Hydroxy hippuric acid
4-Hydroxymandelic acid
4-Hydroxyphenyl acetic acid
4-Hydroxyphenyl lactic acid
4-Hydroxyphenyl pyruvic acid
5-(3′,4′-Dihydroxyphenyl)-γ-Valerolactone
5-(3'-Hydroxyphenyl)-γ-Valerolactone
5,6-Dihydroxy indole
5-Hydroxy tryptophan
5-Hydroxy tryptophol
5-Hydroxyindole
5-Hydroxyindoleacetic acid
5-Hydroxy-N-methyl tryptamine
5-Methoxy tryptamine
5-Methoxy tryptophol
6-Hydroxy melatonin
8-Hydroxy quinaldic acid
Anserine
Anthranilic acid
Benzoic aicd
Carnosine
Dopamine
Epinephrine
Ergothioneine
FIGLU
Hippuric acid
Hisitidine
Histamine
Histidinol
Homogentisic acid
Homovanillic acid
Imidazole acetic acid
Imidazole carboxaldehyde
Imidazole lactic acid
Imidazole propionic acid
Imidazole pyruvic acid
Indole acetamide
Indole acetic acid
Indole acetylglutamine
Indole acrylic acid
Indole butyric acid
Indole carboxaldehyde
Indole carboxylic acid
Indole ethanol (tryptophol)
Indole lactic acid
Indole propionic acid
Indole pyruvic acid
Kynurenic acid
Kynurenine
L-DOPA
Melatonin
Metanephrine
Methyl-4-hydroxybenzoic acid
N1-Methyl histamine
N-Acetyl phenylalanine
N-Acetyl tryptophan
N-Acetyl tyramine
N-Acetyl tyrosine
N-Acetyl-3-hydroxyindole
N-Formyl anthranilic acid
N-Formyl Kynurenine
N-Lactoyl Phenylalanine
N-Lactoyl tyrosine
N-Methyl tryptamine
N-Methyl tyramine
Norepinephrine
Normetanephrine
Octopamine
p-Coumaric acid
Phenyl acetic acid
Phenyl acetyl-L-Glutamine
Phenyl lactic acid
Phenyl propionic acid
Phenyl pyruvic acid
Phenylalanine
Pipecolic acid
Prephenic acid
Protocatechuic acid
Pyrocatechuic acid
Quinaldic acid
Quinolinic acid
Salicyluric acid
Serotonin
Synephrine
Tryptamine
Tryptophanol
Typtophan
Tyramine
Tyrosine
Tyrosine methyl ester
Urocanic acid
Vanillactic acid
Vanillic acid
Vanillylmandelic acid
Xanthurenic acid