UVic Genome BC Protein Centre

Providing service and support for protein identification, characterization, quantitation for biomarker discovery and validation

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Publications

MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma.

Proteomics. 2012 Apr;12(8):1222-43. doi: 10.1002/pmic.201100568.
Domanski D, Percy AJ, Yang J, Chambers AG, Hill JS, Freue GV, Borchers CH.
Comparison of standard- and nano-flow liquid chromatography platforms for MRM-based quantitation of putative plasma biomarker proteins.

Anal Bioanal Chem. 2012 May 1. [Epub ahead of print]
Percy AJ, Chambers AG, Yang J, Domanski D, Borchers CH.
A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1).

Biochim Biophys Acta. 2012 Apr 16. [Epub ahead of print]
Clarke KJ, Adams AE, Manzke L, Pearson TW, Borchers CH, Porter RK.
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.

Nat Med. 2012 Apr 15;18(5):774-82. doi: 10.1038/nm.2728.
Eckle T, Hartmann K, Bonney S, Reithel S, Mittelbronn M, Walker LA, Lowes BD, Han J, Borchers CH, Buttrick PM, Kominsky DJ, Colgan SP, Eltzschig HK.
Structure and Dynamics of Small Soluble Abeta(1-40) Oligomers Studied by Top-Down Hydrogen Exchange Mass Spectrometry.

Biochemistry. 2012 May 1;51(17):3694-703. Epub 2012 Apr 16
Pan J, Han J, Borchers CH, Konermann L.

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