The hPDQ project calls for anti-peptide antibody library to map human proteome

Understandably such has stirred proteomic experts, medical researchers and the scientific community with a buzz of excitement. Featured in this months Proteomonitor the hPDQ project continues to advance the “omic” frontier of science.

The Human Proteome Detection and Quantitation Project:hPDQ (recently published in MCP)proposes comprehensive quantitative coverage of the human proteome through a vast anti-peptide antibody library. By combining immuno-affinity enrichment of peptides that surrogate proteins with MS techniques (SISCAPA and iMALDI), hPDQ could quantitate the protein products of the ~20,500 human genes to produce a map of the human proteome. The paper coauthored by the Centre’s director, Dr. Christoph Borchers, UVic researcher Dr. Terry Pearson and Proteomics experts, such as Dr. Ruedi Aebersold, would have immense implication extending through clinical biomarker discovery, advanced diagnostic assays, drug design and development and ultimately personalized medicine.

Further information can be found in the hPDQ Proteomonitor article or see the full hPDQ project paper.